Stand Up To Cancer (SU2C), the fundraising campaign set up by Cancer Research UK and Channel 4, has teamed up with Xbox to ask gamers around the UK to take a different challenge to raise money for cancer research.

The ad is fronted by Xbox’s most popular exclusive character, Halo’s Master Chief, who calls on gamers to ‘make their next game count’ and take on the challenge of approaching their favourite games in a new way.

Gamers can sign up to ‘Game On’ on the SU2C website and begin fundraising for their gaming challenge. Challenges suggested include ‘The Reverso Challenge’, where players drive in reverse on Forza Horizon 4, and the ‘Projectiles Only Challenge’ on Ori and the Will of the Wisps.

“It is both an honour and privilege to participate in Stand Up To Cancer’s Game On campaign this year. Like so many others, I have personally witnessed cancers devastating effects… That is why this campaign is so important,” said Steve Downes, voice of Master Chief.

“Being the voice of the Master Chief for 20 years has been an epic journey, and Ive seen the positive impact this heroic character has had on so many people all over the world. But his battles could not be won without the help of others. The Chief is calling on you to take down an enemy even stronger than the Flood or the Covenant. It is a battle that can be won. I have seen it with my own eyes. It is time to Stand Up To Cancer.”

In the week beginning 21 September, some of the UK’s top gamers will take on challenges of their own as SU2C takes over Xbox On’s Twitch streaming platform. These influencers, who will be unveiled on Xbox and SU2C social channels in the coming week, will go head-to-head with the Xbox On team.